Research

The focus of this research area is the development of analytical methods and techniques for proteomics as well as for genomics. Methods frequently used in biochemistry are not always well understood or optimised, and most often they are slow, time consuming and laborious. This holds true in particular for reliable, high quality, high throughput methods and techniques for sample preparation, separation and detection. Improvements are urgently needed. Therefore, it is the aim of this working group to contribute to the development of modern and efficient labelling techniques, e.g. for element-tagging of proteins as a marker for selected proteins and of multiplexing detection techniques by use of molecular labels to identify genetic modifications of DNA. Development and application of labelling for imaging of 2D Polyacryl Gel Electrophoresis (PAGE) separated proteins by means of fluorescence and mass spectrometry is a first milestone of the new established group.